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  1. 紀要
  2. 札幌医学雑誌
  3. 93巻

Psychological impact and genetic counseling in patients with multiple endocrine neoplasia type 1(MEN1): addressing quality of life concerns

https://doi.org/10.15114/smj.93.65
https://doi.org/10.15114/smj.93.65
482cd2b2-5620-4f89-b26e-97703172b3f3
名前 / ファイル ライセンス アクション
0036472X93165.pdf 0036472X93165.pdf (1.2 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2024-09-25
タイトル
タイトル Psychological impact and genetic counseling in patients with multiple endocrine neoplasia type 1(MEN1): addressing quality of life concerns
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Multiple endocrine neoplasia type 1
キーワード
言語 en
主題Scheme Other
主題 quality of life
キーワード
言語 en
主題Scheme Other
主題 anxiety
キーワード
言語 en
主題Scheme Other
主題 genetic counseling
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
ID登録
ID登録 10.15114/smj.93.65
ID登録タイプ JaLC
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 Sachiko, MIYAZAKI

× Sachiko, MIYAZAKI

en Sachiko, MIYAZAKI

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Kentaro,SUDA

× Kentaro,SUDA

en Kentaro,SUDA

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Masanori, ITO

× Masanori, ITO

en Masanori, ITO

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Masanori, YAMAZAKI

× Masanori, YAMAZAKI

en Masanori, YAMAZAKI

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Shinya, UCHINO

× Shinya, UCHINO

en Shinya, UCHINO

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Akihiro, SAKURAI

× Akihiro, SAKURAI

en Akihiro, SAKURAI

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内容記述
内容記述タイプ Abstract
内容記述 Multiple endocrine neoplasia type 1(MEN1)is an autosomal dominantly inherited disease that causes tumors in various endocrine and non-endocrine organs and requires cross-sectional and long-term healthcare management.In patients with MEN1, anxiety affects quality of life(QOL), not only because of concerns about health care, but also due to the hereditary nature of the disease. In this study, we examined the psychological impact of MEN1 on patients and the influence of genetic counseling(GC). After conducting a preliminary survey, a questionnaire battery was sent to MEN1 patients recruited from 3 medical institutions and a patient association in Japan. Responses from 76 patients were analyzed(response rate 54%). High correlation coefficients were found between the Mental health subscale of the 36-Item Short Form Health Survey version 2 as a standardized QOL scale and two anxiety scales, the Hospital Anxiety and Depression Scale and State-Trait Anxiety Inventory. The highest component of anxiety concerned “transmission to children and grandchildren”, which was significantly higher in the group that received GC. Low QOL has been reported in patients with MEN1. Although GC provides psychological support, the information provided additional to genetic information may increase anxiety. Thus, while the usefulness of GC in hereditary diseases is widely recognized, to ensure its value for individuals, it is necessary to consider each person’s background and emotional state and bear in mind its possible risks.
言語 en
bibliographic_information ja : 札幌医学雑誌
en : The Sapporo Medical Journal

巻 93, 号 1-6, p. 65-78, ページ数 14, 発行日 2024-09-30
item_7_source_id_7
収録物識別子タイプ ISSN
収録物識別子 0036-472X
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
その他の言語のタイトル
その他のタイトル 多発性内分泌腫瘍1 型(MEN1)患者における心理的影響と 遺伝カウンセリング(GC):生活の質に関する懸念への対応
言語 ja
出版者
出版者 札幌医科大学
言語 ja
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Ver.2 2025-05-20 04:07:09.926161
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