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Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis
https://sapmed.repo.nii.ac.jp/records/17535
https://sapmed.repo.nii.ac.jp/records/17535f3fe3333-3ea3-42b8-8c00-b4af5aacac89
名前 / ファイル | ライセンス | アクション |
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0036472X90164.pdf (1.0 MB)
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Item type | その他 / Others(1) | |||||
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公開日 | 2022-03-18 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
資源タイプ | other | |||||
著者 |
Kazuya, ISHIGURO
× Kazuya, ISHIGURO× Hiroshi, KITAJIMA× Takeshi, NIINUMA× Reo, MARUYAMA× Naotaka, NISHIYAMA× Hitoshi, OHTANI× Gota, SUDO× Mutsumi, TOYOTA× Hajime, SASAKI× Eiichiro, YAMAMOTO× Masahiro, KAI× Hiroshi, NAKASE× Hiromu, SUZUKI |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 多発性骨髄腫(MM)において,ヒストンメチル化酵素EZH2とG9aの共阻害は,インターフェロンシグナルの活性化とMMの重要な生存シグナルであるIRF4-MYCシグナルの抑制を介して,腫瘍増殖を抑制し,細胞周期停止とアポトーシスを誘導することを明らかにした. | |||||
書誌情報 |
札幌医学雑誌=The Sapporo Medical Journal en : The Sapporo Medical Journal 巻 90, 号 1-6, p. 64-65, 発行日 2022-03-31 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0036-472X | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 札幌医科大学 |