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Effects of Cholesteryl Hemisuccinate on the Phalloidin Sensitivity of Normal and Preneoplastic Rat Hepatocytes
https://doi.org/10.15114/tr.23.59
https://doi.org/10.15114/tr.23.5941751902-1ea2-4700-ae0c-448a88cf0b2b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
n004140932359.pdf (243.4 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2019-07-31 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Effects of Cholesteryl Hemisuccinate on the Phalloidin Sensitivity of Normal and Preneoplastic Rat Hepatocytes | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Cholesteryl hemisuccinate | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Phosphatidylcholine | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Phalloidin sensitivity | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Preneoplastic hepatocytes | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| ID登録 | ||||||||||||
| ID登録 | 10.15114/tr.23.59 | |||||||||||
| ID登録タイプ | JaLC | |||||||||||
| 著者 |
Mitaka, Toshihiro
× Mitaka, Toshihiro
× Furukawa, Kazunori
× Tsukada, Hideyuki
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Normal and preneoplastic hepatocytes were isolated from the untreated liver and carcinogen-induced hyperplastic liver nodules of rats, respectively. Phalloidin sensitivity of the 1-hour cultured cells decreased in the presence of cholesteryl hemisuccinate (CH). This was seen more markedly in the order of peneoplastic hepatocytes positive in gamma-glutamyltransferase (GGT), the preneoplastic cells negative in GGT, GGT-positive normal hepatocytes, and GGT-negative normal hepatocytes. Coexistence of phosphatidylcholine and CH inhibited the CH-inducible decrease completely in GGT-negative normal hepatocytes and partially in the normal cells positive in GGT, but failed to recover the decrease in both GGT-negative and positive preneoplastic hepatocytes. These phenomena are suggested to be ascribed to the differences of the cell membrane fluidity among these cells. | |||||||||||
| 書誌情報 |
Tumor Research en : Tumor Research 巻 23, p. 59-64, 発行日 1988 |
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| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 0041-4093 | |||||||||||
| 著者版フラグ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | Sapporo Medical University | |||||||||||
