{"created":"2023-05-15T09:07:03.768900+00:00","id":14290,"links":{},"metadata":{"_buckets":{"deposit":"baa33971-6eb6-4230-8d4b-23b5e5909927"},"_deposit":{"created_by":15,"id":"14290","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"14290"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00014290","sets":["1658:1661:1716"]},"author_link":["24093","24094","24095"],"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1988","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"64","bibliographicPageStart":"59","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"Tumor Research"},{"bibliographic_title":"Tumor Research","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Normal and preneoplastic hepatocytes were isolated from the untreated liver and carcinogen-induced hyperplastic liver nodules of rats, respectively. Phalloidin sensitivity of the 1-hour cultured cells decreased in the presence of cholesteryl hemisuccinate (CH). This was seen more markedly in the order of peneoplastic hepatocytes positive in gamma-glutamyltransferase (GGT), the preneoplastic cells negative in GGT, GGT-positive normal hepatocytes, and GGT-negative normal hepatocytes. Coexistence of phosphatidylcholine and CH inhibited the CH-inducible decrease completely in GGT-negative normal hepatocytes and partially in the normal cells positive in GGT, but failed to recover the decrease in both GGT-negative and positive preneoplastic hepatocytes. These phenomena are suggested to be ascribed to the differences of the cell membrane fluidity among these cells.","subitem_description_type":"Abstract"}]},"item_7_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15114/tr.23.59","subitem_identifier_reg_type":"JaLC"}]},"item_7_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Sapporo Medical University"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0041-4093","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Mitaka, Toshihiro"}],"nameIdentifiers":[{"nameIdentifier":"24093","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Furukawa, Kazunori"}],"nameIdentifiers":[{"nameIdentifier":"24094","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsukada, Hideyuki"}],"nameIdentifiers":[{"nameIdentifier":"24095","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-31"}],"displaytype":"detail","filename":"n004140932359.pdf","filesize":[{"value":"243.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"n004140932359.pdf","url":"https://sapmed.repo.nii.ac.jp/record/14290/files/n004140932359.pdf"},"version_id":"bce85732-db64-47b7-9e0a-302387bbf5ed"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cholesteryl hemisuccinate","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Phosphatidylcholine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Phalloidin sensitivity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Preneoplastic hepatocytes","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of Cholesteryl Hemisuccinate on the Phalloidin Sensitivity of Normal and Preneoplastic Rat Hepatocytes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of Cholesteryl Hemisuccinate on the Phalloidin Sensitivity of Normal and Preneoplastic Rat Hepatocytes","subitem_title_language":"en"}]},"item_type_id":"7","owner":"15","path":["1716"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-07-31"},"publish_date":"2019-07-31","publish_status":"0","recid":"14290","relation_version_is_last":true,"title":["Effects of Cholesteryl Hemisuccinate on the Phalloidin Sensitivity of Normal and Preneoplastic Rat Hepatocytes"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-12-13T02:47:00.998079+00:00"}