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HDAC inhibitors as radiosensitizers
https://doi.org/10.15114/tr.41.15
https://doi.org/10.15114/tr.41.1589e40393-b51b-4c3f-8c7e-4ec702ecb874
名前 / ファイル | ライセンス | アクション |
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n0041409341115.pdf (139.0 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2019-07-31 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | HDAC inhibitors as radiosensitizers | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Histone deacetylase (HDAC) inhibitors | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Histone acetylation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | JNK | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Radiosensitivity | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Apoptosis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.15114/tr.41.15 | |||||
ID登録タイプ | JaLC | |||||
著者 |
Zhang, Yubin
× Zhang, Yubin× Adachi, Masaaki× Kawamura, Rina× Liu, Yaohua× Imai, Kohzoh× Hareyama, Masato× Shinomura, Yasuhisa |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Radiation therapy is one of the main anticancer therapies. However, there are considerable numbers of radioresistant carcinoma cells and severe adverse effects occasionally occur after radiation therapy. Therefore, there have been many attempts to identify radiosensitizers. Histone hyperacetylation has begun to receive considerable attention as a potential target for radiosensitization. Inhibitors of histone deacetylase (HDAC) activity are becoming a major tool for modifying histone acetylation status. This article reviews the classification of HDAC inhibitors and their potential as radiosensitizers. We also discuss possible molecular mechanisms by which the HDAC inhibitors radiosensitize cancer cells. | |||||
書誌情報 |
Tumor Research en : Tumor Research 巻 41, p. 15-21, 発行日 2006 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0041-4093 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Sapporo Medical University |