@article{oai:sapmed.repo.nii.ac.jp:00008139,
 author = {佐藤, 憲市 and 伊東, 民雄 and 尾崎, 義丸 and 石井, 康博 and 福岡, 誠二 and 中川原, 譲二 and 中村, 博彦},
 issue = {1},
 journal = {北海道脳神経疾患研究所医誌 = Journal of Hokkaido Brain Research Foundation},
 month = {Mar},
 note = {In order to differentiate recurrent tumor from radiation necrosis, we performed thallium-201 SPECT (Tl-SPECT) and 18F-fluorodeoxy-glucose PET (FDG-PET) in 6 patients (7 lesions) with malignant brain tumors. Five patients underwent surgery and radiation therapy. One patient underwent radiation therapy. Four patients with metasta tic brain tumor (one patient with 2 lesions), one patient with diffuse astrocytoma and one patient with pineal lesion tumor were retrospectively studied. FDG-PET was assessed as standardized uptake value (SUV). The Tl index was expressed as the count rate over the contralateral normal lesion. Final diagnosis of 7 lesions was recurrent tumor (n=3), combination of recurrent tumor and radiation necrosis (n=2), radiation necrosis (n=2), based on re-operation. The lesion showed high uptake of 18F-FDG was recurrent metastatic brain tumor. Combination of recurrent tumor and radiation necrosis showed relative low uptake of 18F-FDG. Radiation necrosis revealed no uptake of 18F-FDG. However, there were no certain tendencies of Tl index. In metastatic brain tumor, FDG-PET may be useful in differentiating recurrent tumor from radiation necrosis. Tl index was not effective for differentiating recurrent tumor from radiation necrosis.},
 pages = {75--79},
 title = {18F-FDG-PETと201Tl-SPECTによる再発脳腫瘍と放射線壊死の鑑別診断},
 volume = {16},
 year = {2006}
}