{"created":"2023-05-15T09:03:46.838961+00:00","id":8131,"links":{},"metadata":{"_buckets":{"deposit":"f586d985-6250-4bdb-bec5-7db889c72358"},"_deposit":{"created_by":14,"id":"8131","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"8131"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00008131","sets":["1875:1892:1906"]},"author_link":["6576","6577","6578","6579","6580","6581","6582","6583"],"item_2_alternative_title_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Clinical Findings of Transient Global Amnesia : Neuropsychological and Neuroimaging Studies of 169 Patients"}]},"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"26","bibliographicPageStart":"17","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"北海道脳神経疾患研究所医誌 = Journal of Hokkaido Brain Research Foundation"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We evaluate epidemiology, neuropsychology and neuroimaging of transient global amnesia (TGA). There are 169 patients and 175 attacks, the male to female ratio is 1 to 2.3. The mean age of the 175 attacks is 62.1 years. The majority of patients present a single attack. 14 patients (8%) have more than one attack. The mean duration of attacks is 6.7 hours and mean length of retrograde amnesia during the attack is 626.1 days. The precipitating factors are emotional stress, somatosensory input (such as cold weather exposure, swimming, bathing and painful experience) and vasovagal input (such as vomiting and severe cough). 72.7% of TGA attacks have that preceding event. Randt memory test were performed for 74 attacks of 72 patients. After attack all patients felt that they had returned to 'normal', however there were still mild memory impairment that were gradually improved. ECD-SPECT studies were performed for 30 attacks of 29 patients. We compared them with normal control using statistic soft eZIS. The hypoperfusion areas were mesial temporal, cingulate gyrus, lateral temporal, base of forebrain, brainstem and thalamus. We also evaluated ECD-SPECT in 16 patients for using subtracted images during and after TGA attack. The hypoperfusion area during attacks were cingulate, mesial temporal and thalamus. These influenced areas were not consistent with cerebral vascular territories. In 17.6% TGA patients, spotty high intensity areas of DWI-MRI were detected on hippocampus within 48 hours after attack. We conclude TGA is not due to cerebrovascular disease of the arterial thrombo-embolic type, because neuroimaging findings were not supported. The hypoperfusion areas during TGA were usually bilateral limbic areas. We suggest TGA is due to transient hypoperfusion of limbic system triggered by emotion, somatosensory input and autonomic input. Some patient might to have irreversible changes in hippocampus after TGA attacks.","subitem_description_type":"Abstract"}]},"item_2_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"中村記念病院"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1340-5764","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大里, 敦子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐光, 一也"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"溝渕, 雅広"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"村上, 宣人"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"阿部, 剛典"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松下, 隆司"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"川口, 真己"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田中, 千春"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-21"}],"displaytype":"detail","filename":"n1340576416117.pdf","filesize":[{"value":"5.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"n1340576416117.pdf","url":"https://sapmed.repo.nii.ac.jp/record/8131/files/n1340576416117.pdf"},"version_id":"dc282969-550a-4967-8134-ee19f994cf76"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"transient global amnesia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Randt memory test","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"SPECT","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DWI","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"一過性全健忘の臨床的検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"一過性全健忘の臨床的検討","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"14","path":["1906"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-03-24"},"publish_date":"2009-03-24","publish_status":"0","recid":"8131","relation_version_is_last":true,"title":["一過性全健忘の臨床的検討"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-12-13T03:15:59.942320+00:00"}