@article{oai:sapmed.repo.nii.ac.jp:00008032,
 author = {井出, 渉 and 佐々木, 雄彦 and 和田, 啓二 and 中村, 順一 and 末松, 克美},
 issue = {1},
 journal = {北海道脳神経疾患研究所医誌 = Journal of Hokkaido Brain Research Foundation},
 month = {Aug},
 note = {In attempt to dissolve the cisternal clot early and to reduce occurrence of the cerebral vasospasm, continuous cisternal irrigation was applied in patients with subarachnoid hemorrhage due to ruptured cerebral aneurysm. Ventricular catheter and cisternal draining catheter were positioned at the time when clipping of aneurysm was performed. Occasionally intrasylvian catheter was positioned simultaneously, when sylvian cistern was packed with thick clot. Irrigation solution with Urokinase(Plaminogen activator) is infused from sylvan and/or vantricular catheter while bloody CSF is withdrawn from cisternal draining catheter within 7th postoperative day. Clots in perimesencephalic cistern, sylvian vallecula were well dissolved and removed by ventricular-cisternal irrigation, but insular cisternal clots were washed out more effectively in combination with sylvian-cisternal irrigation. Cisternal irrigation seemed to reduce occurrence or severity of cerebral vasospasm.},
 pages = {76--80},
 title = {破裂脳動脈瘤に対するウロキナーゼ脳槽灌流療法},
 volume = {3},
 year = {1990}
}