{"created":"2023-05-15T09:03:38.144820+00:00","id":7996,"links":{},"metadata":{"_buckets":{"deposit":"3a8a9b0c-9ea7-498a-bda3-d53d30103758"},"_deposit":{"created_by":14,"id":"7996","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"7996"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00007996","sets":["1875:1892:1893"]},"author_link":["5873","5874","5875","5876","5877","5878","5879"],"control_number":"7996","item_2_alternative_title_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Relationship Between the Anaplasia in Glioma and Its Staining Attitude of GFAP, Vimentin — Immunohistological examination with GFAP and Vimentin —"}]},"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1988-08-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"北海道脳神経疾患研究所医誌 = Journal of Hokkaido Brain Research Foundation"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The authors have already reported that vimentin is a marker of immature glial cells. The study was performed by the immunohistological examination of developing human and rat embryonic spinal cord. The purpose of the present study is to investigate how the attitude of GFAP and vimentin in developing human and rat embryonic spinal cord reflects upon the anaplastic process of gliomas. Surgical specimens (astrocytoma Grade- II : 21, astrocytoma Grade- III : 28, astrocytoma Grade- IV : 4, oligodendroglioma : 6, medulloblastoma : 3, subependymoma : 1) were fixed in ethanol and embedded in paraffin. Paraffin sections were stained with anti- GFAP rabbit serum, anti vimentin mouse monoclonal antibody according to PAP methods and ABC methods. In astrocytoma Grade- II , many tumor cells were GFAP and vimentin positive. In astrocytoma Grade- III and IV, GFAP and vimentin positive tumor cells were less frequent and the attitude of vimentin staining was various. In medulloblastoma, tumor cells were GFAP and vimentin negative and stained cells wei-e identified only among suspected reactive astrocytes. These results indicate that vimentin is not considered to be a marker of anaplasia in gliomas and that morphological variability within malignant gliomas is attributed to Cataplastic changes.","subitem_description_type":"Abstract"}]},"item_2_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"中村記念病院"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1340-5764","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鎌田, 一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"荒, 清次"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"伊東, 民雄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岡田, 好生"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"堀田, 隆史"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中村, 順一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"末松, 克美"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-21"}],"displaytype":"detail","filename":"n13405764111.pdf","filesize":[{"value":"3.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"n13405764111.pdf","url":"https://sapmed.repo.nii.ac.jp/record/7996/files/n13405764111.pdf"},"version_id":"a39fdbad-f0c3-4955-bad3-05af2a8889b4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"GFAP","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"vimentin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"glioma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"anaplasia","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"GliomaにおけるAnaplasiaとGFAP, Vimentinの染色態様との関連 : GFAP, Vimentinによる免疫組織学的検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"GliomaにおけるAnaplasiaとGFAP, Vimentinの染色態様との関連 : GFAP, Vimentinによる免疫組織学的検討","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"14","path":["1893"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-03-24"},"publish_date":"2009-03-24","publish_status":"0","recid":"7996","relation_version_is_last":true,"title":["GliomaにおけるAnaplasiaとGFAP, Vimentinの染色態様との関連 : GFAP, Vimentinによる免疫組織学的検討"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2024-02-21T00:21:46.104120+00:00"}