{"created":"2023-05-15T09:03:35.719514+00:00","id":7958,"links":{},"metadata":{"_buckets":{"deposit":"154f195b-d8bb-4b58-bc0b-60ebd8c1ff54"},"_deposit":{"created_by":15,"id":"7958","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"7958"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00007958","sets":["1674:1675:1676"]},"author_link":["5672","5673","5674","5675","5676","5677","5678"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-11-29","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"113","bibliographicPageStart":"113","bibliographicVolumeNumber":"52","bibliographic_titles":[{"bibliographic_title":"北海道立衛生研究所報 = Report of the Hokkaido Institute of Public Health"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"肝炎を自然発症するLECラットにおいてDNA単鎖切断に及ぼす銅の蓄積の影響を調べた。LECラットの肝臓において銅と鉄は4週齢から15週齢に蓄積した。低鉄食で飼育したラットでは鉄の蓄積は認められなかったが、銅の蓄積は普通食のラットと同様量認められた。肝細胞のDNA単鎖切断の量はcomet法を用いて検出した。テールが認められた細胞の頻度とテールの長さの平均値を求めたところ、低鉄食を与えたLECラットの肝細胞と普通食を与えたLECラットの間にほとんど違いは認められなかった。これらの結果からLECラットの肝細胞におけるDNA損傷の誘発には鉄の蓄積は関与していないことが示唆された。","subitem_description_type":"Abstract"}]},"item_2_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"北海道立衛生研究所"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0441-0793","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hayashi, Masanobu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kuge, Tomoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Endoh, Daiji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakayama, Kenji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Arikawa, Jiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takazawa, Akira"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okui, Toyo"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-21"}],"displaytype":"detail","filename":"n0441079352103.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"n0441079352103.pdf","url":"https://sapmed.repo.nii.ac.jp/record/7958/files/n0441079352103.pdf"},"version_id":"0068b0dc-25e4-48c1-972f-3a53080b5a67"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Hepatic iron Accumulation Is Not Directly Associated with Induction of DNA Strand Breaks in the Liver Cells of Long-Evans Cinnamon（LEC) Rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Hepatic iron Accumulation Is Not Directly Associated with Induction of DNA Strand Breaks in the Liver Cells of Long-Evans Cinnamon（LEC) Rats","subitem_title_language":"en"}]},"item_type_id":"2","owner":"15","path":["1676"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-03-23"},"publish_date":"2009-03-23","publish_status":"0","recid":"7958","relation_version_is_last":true,"title":["Hepatic iron Accumulation Is Not Directly Associated with Induction of DNA Strand Breaks in the Liver Cells of Long-Evans Cinnamon（LEC) Rats"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-12-13T04:39:55.487127+00:00"}