@article{oai:sapmed.repo.nii.ac.jp:00016398, author = {Masaki, Yamamoto and Tsukasa, Hori and Naoki, Hatakeyama and Keita, Igarashoi and Natsuko, Inazawa and Nobuhiro, Suzuki and Norio, Takei and Yoichi, M. Ito and Kimikazu, Matsumoto and Koji, Kato and Hiroyuki, Tsutsumi and Yasuo, Kokai}, issue = {1-6}, journal = {札幌医学雑誌 = The Sapporo Medical Journal, The Sapporo medical journal}, month = {}, note = {To explore the role of Chemokine (C-C motif) ligand 8 (CCL8) as a potential biomarker for acute graft-versus-host disease (aGVHD), we retrospectively analyzed the sera and clinical course of 31 patients with grade II–IV aGVHD. No deaths occurred in the ten patients with serum CCL8 concentrations less than 213 pg/mL, whereas 11 of the 21 patients with more than 213 pg/mL died within 180 days post-transplantation. This landmark analysis revealed a significantly lower urvival rate of patients with a CCL8 serum concentration greater than 213 pg/mL. Thus, elevated serum CCL8 concentration before day 100 post-transplantation may predict aGVHD prognosis}, pages = {45--51}, title = {Early expression of serum CCL8 closely correlates to non-relapse mortality after allogeneic hematopoietic stem cell transplantation}, volume = {86}, year = {2017} }