{"created":"2023-05-15T09:08:37.003680+00:00","id":16256,"links":{},"metadata":{"_buckets":{"deposit":"cd3704b3-4b40-44b8-82a7-3c69701a8a4f"},"_deposit":{"created_by":15,"id":"16256","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"16256"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00016256","sets":["1658:1766:1850"]},"author_link":["31553","31554","31555","31556","31549","31550","31551","31552"],"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"41","bibliographicPageStart":"35","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"札幌医科大学保健医療学部紀要 = Bulletin of School of Health Sciences Sapporo Medical University"},{"bibliographic_title":"Bulletin of School of Health Sciences Sapporo Medical University","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The purpose of this study was to investigate effects of fiber type composition on resting ATP turnover at ischemic rest in human gastrocnemius (GC), tibialis anterior (TA) and soleus (SL) muscles using continuous-wave near-infrared spectroscopy (NIRS). Fiber type composition of the muscles was evaluated by histochemical analysis of muscle biopsies. Type I fiber occupied 54.0 ± 5.3, 62.2 ± 2.6 (p< 0.05) and 87.7 ± 3.3 % (p < 0.01, p < 0.05) of total fiber cross-section area in GC, TA and SL, respectively. Initial rate of decrease in muscle oxygenation by NIRS during ischemia was converted to resting ATP turnover rate using by muscle oxygen store at rest and a phosphate-to-oxygen ratio of 5.5. Resting ATP turnover rate was also corrected for muscle temperature decrease during the ischemic period. It was 0.281 ± 0.046, 0.277 ± 0.022 and 0.366 ± 0.046 mmol・(kg wet wt)-1・min-1 in GC, TA and SL, respectively. Resting ATP turnover rate correlated with the relative type I fiber area (r = 0.748, p < 0.01) for the pooled data of all three muscles. It is suggested that the relative type I fiber area is an important factor determining resting metabolic rate in human muscles in vivo. 本研究の目的は近赤外線分光法を用いて、虚血された腓腹筋、前脛骨筋およびヒラメ筋における安静時のATP代謝速度と筋線維組成の関係を検討することである。腓腹筋、前脛骨筋およびヒラメ筋の遅筋線維占有率はそれぞれ54.0 ± 5.3、62.2 ± 2.6（p < 0.05）および87.7 ± 3.3％（p < 0.01, p < 0.01）であった。近赤外線分光法によって測定された虚血初期の筋酸素化レベルの低下率は、安静時における筋内酸素貯蔵量とリン酸／酸素比（5.5）を用いて、安静時ATP代謝速度に変換された。また、安静時ATP代謝速度を、虚血時における筋温の低下を考慮して補正した。腓腹筋、前脛骨筋およびヒラメ筋における安静時ATP代謝速度はそれぞれ、0.281 ± 0.046、0.277 ± 0.022および0.366 ± 0.046 mmol（kg wet wt）?1・min?1であった。各筋の値をまとめると、安静時のATP代謝速度は遅筋線維占有率と有意な正の相関関係（r = 0.748, p < 0.01）にあった。以上の結果から、遅筋線維占有率はin vivoの測定においても、安静時代謝量を決定する重要な要因であると示唆される。","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"31553","nameIdentifierScheme":"WEKO"}],"names":[{"name":"神林, 勲"}]},{"nameIdentifiers":[{"nameIdentifier":"31554","nameIdentifierScheme":"WEKO"}],"names":[{"name":"武田, 秀勝"}]},{"nameIdentifiers":[{"nameIdentifier":"31555","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Aivaras, Ratkevicius"}]},{"nameIdentifiers":[{"nameIdentifier":"31556","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Bjorn, Quistorff"}]}]},"item_7_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15114/bshs.6.35","subitem_identifier_reg_type":"JaLC"}]},"item_7_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"札幌医科大学保健医療学部"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1344-9192","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Isao, KAMBAYASHI"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Aivaras, RATKEVICIUS"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hidekatsu, TAKEDA"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Bjorn, QUISTORFF"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-09-11"}],"displaytype":"detail","filename":"n13449192635.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"n13449192635.pdf","url":"https://sapmed.repo.nii.ac.jp/record/16256/files/n13449192635.pdf"},"version_id":"459ee9c6-3d28-4843-ad92-ffb3f18d69bb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"NIRS","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"% type I fibers","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"resting metabolic rate","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ischemia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"近赤外線分光法","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"％タイプⅠ線維","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"安静時代謝","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"前脛骨筋","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Fiber type composition affects resting ATP turnover estimated by NIRS in human ischemic muscle","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Fiber type composition affects resting ATP turnover estimated by NIRS in human ischemic muscle","subitem_title_language":"en"},{"subitem_title":"筋繊維組成は近赤外線分光法により評価されたヒト虚血筋における安静時ATP代謝量に影響を与える","subitem_title_language":"ja"}]},"item_type_id":"7","owner":"15","path":["1850"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-09-11"},"publish_date":"2019-09-11","publish_status":"0","recid":"16256","relation_version_is_last":true,"title":["Fiber type composition affects resting ATP turnover estimated by NIRS in human ischemic muscle"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-12-13T02:54:45.847924+00:00"}