@article{oai:sapmed.repo.nii.ac.jp:00015437, author = {浦沢, 价子 and 秋葉, 澄伯 and 谷口, 孝喜 and 石沢, 文彦 and 千葉, 峻三}, issue = {3}, journal = {札幌医学雑誌 = The Sapporo medical journal, The Sapporo medical journal}, month = {Jun}, note = {Human reovirus-like agent (HRLA) has recently been recognized as one of the causative agents of acute nonbacterial gastroenteritis in infants and children. Ths present report deals with a comparison of sensitivity of two different tests to detect antibody against this agent. The results obtained are as follows: 1. When sera from patients with this disease and their siblings were examined, the results of CF test using human reovirus-like agent as the antigen (HRLA-CF) closely agreed with those of CF test using neonatal calf diarrhea virus as the antigen (NCDV-CF); further, the presence of serum precipitating antibody to NCDV (NCDV-PT), which was detectable by counter-immunoelectro-osmophoresis developed by Middleton et al6) strongly correlated with the presence of HRLA-CF antibody (P<10-8 by Fisher exact test). 2. In general, it was found that when sera obtained shortly after the infection were examined, antibody-positive rate by NCDV-PT test was higher than that by NCDV-CF test; on the other hand, when sera collected from persons who had contracted the disease in the remote past were tested, NCDV-PT test was found to be inferior to NCDV-CF test in the ability to detect the waning antibody.}, pages = {249--256}, title = {Counter-immunoelectro-osmophoresisを用いたレオウイルス様因子に対する血清沈降抗体の検出およびその疫学的意義}, volume = {47}, year = {1978} }