{"created":"2023-05-15T09:07:50.575144+00:00","id":15269,"links":{},"metadata":{"_buckets":{"deposit":"357ef33f-d0c6-4054-bde7-af88cdc0a585"},"_deposit":{"created_by":15,"id":"15269","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"15269"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00015269","sets":["1658:1659:1752"]},"author_link":["28083","28084","28085","28086","28087","28088","28089","28090","28075","28076","28077","28078","28079","28080","28081","28082"],"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1979-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"37","bibliographicPageStart":"30","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"札幌医学雑誌 = The Sapporo medical journal"},{"bibliographic_title":"The Sapporo medical journal","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The effects of a 2 hour coronary perfusion with 0-4℃ Ringer's lactate solution to protect the myocardium from ischemia were studied by comparing with non-protected group. During this procedure, extracorporeal circulation was employed to perfuse the body under mild hypothermia at 30℃. In the protected group of 5 dogs, cardiac arrest was induced after 5 minutes of aortic cross-clamping by coronary perfusion via the aortic root with 0-4℃ Ringer's lactate solution at 150cm H2O gravity. Myocardial temperature was maintained around 15℃ for 2 hours under an ischemic state. In the non protected group of 5 dogs, myocardium was allowed to enter an ischemic state around 27ーC for 2 hours after aortic cross-clamping. Light microscopic findings revealed no ischemic changes such as necrosis of the cells, bleeding or edema of the myocardium in both groups. An electron microscopic examination also revealed no ischemic damage of the cells in the protected group, in contrast, irreversible changes such as severe mitochondrial damage in the non-protected group were seen. No reduction of succinic dehydrogenase activity was revealed in the protected group. However, a marked decrease of the enzymatic activity was observed in the non-protected group. In conclusion, the myocardium was shown to be protected under an ischemic state with a 2 hour administration of cold coronary perfusion from the morphological evaluations in dogs.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"28083","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Katsumi, Ohori"}]},{"nameIdentifiers":[{"nameIdentifier":"28084","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Fumiyuki, Okamoto"}]},{"nameIdentifiers":[{"nameIdentifier":"28085","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yuichi, Iwaki"}]},{"nameIdentifiers":[{"nameIdentifier":"28086","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Michio, Chiba"}]},{"nameIdentifiers":[{"nameIdentifier":"28087","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Hiroaki, Adachi"}]},{"nameIdentifiers":[{"nameIdentifier":"28088","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tomio, Abe"}]},{"nameIdentifiers":[{"nameIdentifier":"28089","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Hiroshi, Ajiki"}]},{"nameIdentifiers":[{"nameIdentifier":"28090","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sakuzo, Komatsu"}]}]},"item_7_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15114/smj.48.30","subitem_identifier_reg_type":"JaLC"}]},"item_7_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"札幌医科大学医学部"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0036-472X","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大堀, 克己"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岡本, 史之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岩城, 裕一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"千葉, 廸夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"安達, 博昭"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"安倍, 十三夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"安喰, 弘"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小松, 作蔵"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-23"}],"displaytype":"detail","filename":"n0036472X48130.pdf","filesize":[{"value":"3.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"n0036472X48130.pdf","url":"https://sapmed.repo.nii.ac.jp/record/15269/files/n0036472X48130.pdf"},"version_id":"12be2108-87b6-4e91-9d63-b7eaf975e395"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"冷却液冠灌流法による心筋保護とその形態学的評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"冷却液冠灌流法による心筋保護とその形態学的評価","subitem_title_language":"ja"},{"subitem_title":"Protection of the Myocardium under an Ischemic State by a Two Hour Cold Coronary Perfusion and Morphological Evaluation","subitem_title_language":"en"}]},"item_type_id":"7","owner":"15","path":["1752"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-08-23"},"publish_date":"2019-08-23","publish_status":"0","recid":"15269","relation_version_is_last":true,"title":["冷却液冠灌流法による心筋保護とその形態学的評価"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-12-13T02:31:24.268661+00:00"}