@article{oai:sapmed.repo.nii.ac.jp:00015264,
 author = {鈴木, 明 and 中村, 光成 and 森, 雅樹 and 森, 拓ニ and 谷内, 昭 and 松本, 博之 and 坂本, 真一 and 金子, 正光 and 李, 鎬汪},
 issue = {supple},
 journal = {札幌医学雑誌 = The Sapporo medical journal, The Sapporo medical journal},
 month = {Mar},
 note = {In the period from January to March 1981, Korean hemorrhagic fever （KHF） developed in 3 laboratory staff members of the Animal Experiment Center of Sapporo Medical College. The disease had an abrupt onset in all of the patients and was accompanied by high fever and chills and, at times, by malaise and anorexia. On admission, physical examinations demonstrated an injected pharynx, myalgia, abdominal tenderness and mild hepatomegaly. Within a few days after initiation of fever, the severest case revealed various signs, including shock, pulmonary congestion, renal failure, myositis and myocarditis. Laboratory examination showed marked proteinuria, leukocy-tosis, an increase in atypical lymphocytes, thrombocytopenia and an elevation of serum GOT, GPT, LDH, CPK, BUN and creatinine. Marked alterations in the coagulation system also developed early in the course of this disease. These abnormalities reached a peak within about 7 days and returned to normal within a few weeks. The degree of laboratory data was parallel to the severity of the disease. Case 1, the severest, had a gradual downhill course and died 54 days after the onset of symptoms. Immunofluorescent antibodies （IF） to KHF virus were tested by Dr. H. W. Lee in a pair serum of all of the patients. All of sera obtained from these patients were positive. Therefore, diagnosis was done on the basis of the clinical features and course and was confirmed by demonstration of IF antibodies to KHF virus.},
 pages = {K7--15},
 title = {流行性出血熱 （韓国型出血熱） の3症例},
 volume = {51},
 year = {1982}
}