{"created":"2023-05-15T09:07:22.374551+00:00","id":14719,"links":{},"metadata":{"_buckets":{"deposit":"54ce6b62-70ed-4370-b93e-8dfd90b934f9"},"_deposit":{"created_by":14,"id":"14719","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"14719"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00014719","sets":["1658:1659:1722"]},"author_link":["25886","25887","25888","25883","25884","25885"],"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"240","bibliographicPageStart":"233","bibliographicVolumeNumber":"60","bibliographic_titles":[{"bibliographic_title":"札幌医学雑誌 = The Sapporo medical journal"},{"bibliographic_title":"The Sapporo medical journal","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Several oncogenes were introduced into a normal mouse osteoblastic cell line, MC3T3- El, by calcium phosphate-mediated DNA transfection. Transformed foci were formed by cotransfection with adenovirus type 12 E1A （Adl2E1A） and activated c-Ha-ras （EJras） oncogenes, and with c-myc and EJras oncogenes. Transfection with c- myc, Ad12E1A or EJras induced no obvious foci. Transformed cell lines established from each trans- formed focus had high saturation densities in culture and were tumorigenic when injected into athy- mic mice with low-differetiated sarcoma. The transfected oncogene DNA sequences were detected in the cellular DNA of all the transformants. Alkaline phosphatase activity decreased in transformants compared to their parental MC3T3-E1 cells.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"25886","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Saito, Yoichi"}]},{"nameIdentifiers":[{"nameIdentifier":"25887","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yoshida, Koichi"}]},{"nameIdentifiers":[{"nameIdentifier":"25888","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yamashita, Tshiharu"}]}]},"item_7_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15114/smj.60.233","subitem_identifier_reg_type":"JaLC"}]},"item_7_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"札幌医科大学医学部"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0036-472X","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"斉藤, 要一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"吉田, 幸一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山下, 利春"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-31"}],"displaytype":"detail","filename":"n0036472X603233.pdf","filesize":[{"value":"3.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"n0036472X603233.pdf","url":"https://sapmed.repo.nii.ac.jp/record/14719/files/n0036472X603233.pdf"},"version_id":"81b4df3d-36c9-4395-b6ad-5368e1948196"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Yamashita, Toshiharu","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Osteoblast","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Oncogene","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Transformation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Alkaline phosphatase","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"癌遺伝子によるマウス骨芽細胞株MC3T3-E1のトランスフォーメーショソ","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"癌遺伝子によるマウス骨芽細胞株MC3T3-E1のトランスフォーメーショソ","subitem_title_language":"ja"},{"subitem_title":"Transformation of Osteoblastic Cell Line MC3T3-E1 with Oncogenes","subitem_title_language":"en"}]},"item_type_id":"7","owner":"14","path":["1722"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-07-31"},"publish_date":"2019-07-31","publish_status":"0","recid":"14719","relation_version_is_last":true,"title":["癌遺伝子によるマウス骨芽細胞株MC3T3-E1のトランスフォーメーショソ"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-12-13T02:24:28.629490+00:00"}