@article{oai:sapmed.repo.nii.ac.jp:00014719,
 author = {斉藤, 要一 and 吉田, 幸一 and 山下, 利春},
 issue = {3},
 journal = {札幌医学雑誌 = The Sapporo medical journal, The Sapporo medical journal},
 month = {Jun},
 note = {Several oncogenes were introduced into a normal mouse osteoblastic cell line, MC3T3- El, by calcium phosphate-mediated DNA transfection. Transformed foci were formed by cotransfection with adenovirus type 12 E1A （Adl2E1A） and activated c-Ha-ras （EJras） oncogenes, and with c-myc and EJras oncogenes. Transfection with c- myc, Ad12E1A or EJras induced no obvious foci. Transformed cell lines established from each trans- formed focus had high saturation densities in culture and were tumorigenic when injected into athy- mic mice with low-differetiated sarcoma. The transfected oncogene DNA sequences were detected in the cellular DNA of all the transformants. Alkaline phosphatase activity decreased in transformants compared to their parental MC3T3-E1 cells.},
 pages = {233--240},
 title = {癌遺伝子によるマウス骨芽細胞株MC3T3-E1のトランスフォーメーショソ},
 volume = {60},
 year = {1991}
}