@article{oai:sapmed.repo.nii.ac.jp:00014712,
 author = {三好, 正幸 and 伊東, 英樹 and 工藤, 隆一},
 issue = {2},
 journal = {札幌医学雑誌 = The Sapporo medical journal, The Sapporo medical journal},
 month = {Apr},
 note = {Identification of cytotrophoblasts （CTs） and syncytiotrophoblasts （STs）, is often difficult cytologically. For clarifying their morphologic features, cytologic examination of normal chorionic villi, hydatidiform moles and invasive moles was performed on scraped and imprinted smears, obtained from the uterine cervix and corpus. The same cells on these smears were examined consecutively by light microscopy （LM）, scanning electron microscopy （SEM） and transmission elec-tron microscopy （TEM）. The findings are presented as follows : 1） SEM examination revealed that in normal chorionic villi, the surface of CTs had an overlap-ping structure like a mica or roof-tile-like structure with occasional small wart-like projections on the surface. In the hydatidiform and invasive moles these features remained unchanged. 2） Under SEM examination of normal chorionic villi, STs had densely packed fine short mi-crovilli （MV） which are regular in shape and spread over the surface, thereby differentiating STs and CTs. The surface features of STs in both hydatidiform and invasive moles were basically similar to those of normal STs, although branched MV slightly increased in number. 3） TEM examination of CTs and STs revealed the same findings on the cell membrane as those obtained by SEM. Consequently the various surface features were useful for differentiation between them. 4） The surface of multinucleated histiocytes, when examined by SEM, had an appearance resem-bling the surface of a floatstone. Consequently SEM examination can easily differentiate multinu-cleated histiocytes from the STs which they resemble on LM examination. 5） In the case of TEM examination on a tissue specimen of invasive mole, the demonstration of long winding membranous protrusions into the intercellular space or regular MV also could provide the basis of identification of their origination from CTs and STs. 6） In comparison with examination by a single method, consecutive LM-SEM-TEM examination of the same cells was more useful for differentiation of CTs, STs and histiocytes.},
 pages = {149--162},
 title = {ヒトの正常絨毛膜絨毛,胞状奇胎,侵入奇胎における剥離細胞の光顕一走査電顕一透過電顕法による鑑別},
 volume = {60},
 year = {1991}
}