@article{oai:sapmed.repo.nii.ac.jp:00014669,
 author = {石井, 勝久 and 田中, 繁道 and 斎藤, 重幸},
 issue = {2},
 journal = {札幌医学雑誌 = The Sapporo medical journal, The Sapporo medical journal},
 month = {Apr},
 note = {A cross-sectional epidemiological study was performed in 628 male inhabitants （aged 30-69 years, mean 56.6±9.8 years） in two rural agricultural towns in Hokkaido, Japan, in order to clarify the relations among adiposity, adipose tissue distribution, plasma insulin levels and cardiovascular risk factors. In 184 men （aged 30-69 years, mean 56.4±9.8 years） who had given consent, the 75g oral glucose tolerance test （OGTT） was done. Variables for analysis were body fat weight to whole body weight ratio （FR） measured by the bioimpedance method （Tanita BF 102）, waist to hip circumference ratio （WHR）, systolic （SBP） and diastolic blood pressure （DBP）, serum total cholesterol （TC）, triglyceride （TG）, HDL cholesterol （HDL）, fasting plasma glucose （FPG）, insulin level at 120 min after OGTT （120IRI）, and sum of insulin levels before and at 60 and 120 min after OGTT （ΣRI）. Hypercholesterolemia, hypertriglyceridemia and hypo-HDL cholesterolemia were defined by TC≧220 mg/dl, TG≧150 mg/dl and HDL<40 mg/dl, respectively. FR correlated positively with SBP, DBP, TC, TG and FPG, and negatively with HDL. SBP, DBP, TC, TG and FPG were significantly higher in the 50% of subjects with FR>median FR than in the group with FR<median FR, while HDL was significantly lower in the high-FR group. The prevalence of HT, impaired glucose tolerance and dyslipidemia were greater in the high-FR group than in the low-FR group. Similar findings were observed in concern with WHR. 120IRI and ΣIRI were correlated positively with FR, WHR, DBP, TC, TG and FPG, and negatively with HDL. Both the high FR group and high WHR group had significantly increased levels of 120IRI and ΣIRI as compared to the lower respective groups. From these results, we concluded that FR and WHR were closely related to plasma insulin levels and cardiovascular risk factors, and that increased adiposity and intraabdominal adipose tissue distribution may play at least some role in deterioration of cardiovascular risk factors mediated by hyperinsulinemia in men.},
 pages = {99--12},
 title = {肥満(体脂肪率),体脂肪分布および高インスリン血症と心血管疾患危険因子の相関に関する疫学的研究},
 volume = {65},
 year = {1996}
}