@article{oai:sapmed.repo.nii.ac.jp:00014242, author = {Yasuda, Motoaki and Shindoh, Masanobu and Kohgo, Takao and Amemiya, Akira and Sawada, Yukiharu and Fujinaga, Kei}, journal = {Tumor Research, Tumor Research}, month = {}, note = {Twenty cases of oral squamous cell carcinoma (SCC) with cervical lymph node metastasis were investigated. Both primary lesions and metastatic lymph nodes were analyzed for the involvement of human papillomavirus (HPV) DNAs utilizing the polymerase chain reaction (PCR) method and dot blot hybridization. HPV DNAs were detected in five cases. Four primary lesions contained HPV-16 DNA, and one contained both HPV-16 and HPV-18 DNAs out of 20 cases examined. No HPV DNAs were detected in metastatic lymph node tissues in cases where HPV DNAs could not be detected in primary cancer tissues. The same types of HPV DNAs as those found in primary lesions were detected in metastatic lymph nodes including those with HPV-16 and HPV-18.}, pages = {29--37}, title = {Human Papillomavirus Genome in Oral Carcinoma and Their Metastatic Cervical Lymph Node Tissues.}, volume = {29}, year = {1994} }