{"created":"2023-05-15T09:07:00.168923+00:00","id":14213,"links":{},"metadata":{"_buckets":{"deposit":"2d75659d-e29c-465e-9882-e145da82669a"},"_deposit":{"created_by":15,"id":"14213","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"14213"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00014213","sets":["1658:1661:1713"]},"author_link":["23640","23641","23642","23643","23644","23645"],"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"13","bibliographicPageStart":"1","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"Tumor Research"},{"bibliographic_title":"Tumor Research","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Cancer-associated retinopathy (CAR) is an ocular manifestation of para-neoplastic syndrome and is further classified into two distinct diseases, CAR and MAR (melanoma-associated retinopathy) . CAR is associated with epithe-lial cancers, mostly lung small cell carcinoma, and is characterized by retini-tis pigmentosa-like retinal degeneration, such as ring scotoma, night blind-ness, and lowering of a and b-waves in electroretinogram (ERG) . Usually CAR can be found before an underlying primary cancer is diagnosed. In con-trast, MAR is associated with cutaneous malignant melanoma and is characte-rized by the relatively sudden onset of photophobia, nyctalopia, and lowering of b-wave in ERG. Histopathological study has revealed that photoreceptor and bipolar degeneration are primarily involved in CAR and MAR, respec-tively. Both CAR and MAR are believed to result from an autoimmune basis. In CAR, a calcium binding protein called recoverin, heat shock cog-nate protein 70 (hsc 70) , and other proteins are identified as retinal autoanti-gens, while the retinal antigens in MAR have not yet been identified. In this text, we review up-to-date information about the clinical and pathological aspects of these diseases.","subitem_description_type":"Abstract"}]},"item_7_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15114/tr.33.1","subitem_identifier_reg_type":"JaLC"}]},"item_7_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Sapporo Medical University"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0041-4093","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Maeda, Akiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Tadao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ogawa, Keiichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maruyama, Ikuyo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakagawa, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohguro, Hiroshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-31"}],"displaytype":"detail","filename":"n00414093331.pdf","filesize":[{"value":"962.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"n00414093331.pdf","url":"https://sapmed.repo.nii.ac.jp/record/14213/files/n00414093331.pdf"},"version_id":"d6f637a1-b1c5-4f13-bf2b-168961134f1e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"CAR","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"MAR","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Recoverin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hsc 70","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Autoimmunity","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Review : Clinical and Pathological Aspects of Cancer-Associated Retinopathy (CAR)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Review : Clinical and Pathological Aspects of Cancer-Associated Retinopathy (CAR)","subitem_title_language":"en"}]},"item_type_id":"7","owner":"15","path":["1713"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-07-31"},"publish_date":"2019-07-31","publish_status":"0","recid":"14213","relation_version_is_last":true,"title":["Review : Clinical and Pathological Aspects of Cancer-Associated Retinopathy (CAR)"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-12-13T02:44:43.496385+00:00"}