@article{oai:sapmed.repo.nii.ac.jp:00014127, author = {三高, 俊広 and 谷水, 直樹 and 市戸, 義久}, issue = {1-6}, journal = {札幌医学雑誌 = The Sapporo medical journal, The Sapporo medical journal}, month = {}, note = {In this review we summarize recent studies that have been performed in our laboratory. We has focused our researches on the issue of the “liver”, i.e., development, stem/progenitor cells, regeneration, and in vitro reconstruction of hepatic tissues. Our researches were mainly divided into 4 themes; (1) liver development, especially, biliary duct formation, (2) stem/progenitor cells related in normal and pathophysiological conditions of liver diseases, (3) cell transplantation for the treatment of liver diseases, and (4) in vitro reconstruction of hepatic tissues. To elucidate the unresolved issues of each theme, we have been investigating by using embryological, molecular biological, and pathological methods. In the near future, we hope that our approaches will lead to the development of new effective medicines and treatments for intractable liver diseases and of an artificial liver device in which the reconstructed hepatic tissues are incorporated.}, pages = {11--18}, title = {肝臓の組織構築と再生}, volume = {82}, year = {2013} }