{"created":"2023-05-15T09:06:47.220800+00:00","id":13760,"links":{},"metadata":{"_buckets":{"deposit":"a6ec8bb6-eb54-4cda-af59-4ba00d47d5b8"},"_deposit":{"created_by":14,"id":"13760","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"13760"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00013760","sets":["1658:1659:1871"]},"author_link":["21611"],"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-6","bibliographicPageEnd":"63","bibliographicPageStart":"62","bibliographicVolumeNumber":"85","bibliographic_titles":[{"bibliographic_title":"札幌医学雑誌 = The Sapporo Medical Journal"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"腫瘍微小環境ストレスがCD8+T細胞応答を介した免疫応答に与える影響に関しては知られていない. 我々は微小環境ストレス（低酸素, グルコース飢餓）により腫瘍細胞表面の非古典的MHC class Ib (Qa-1b, HLA-E)発現が上昇し, 特異的CD8+T細胞応答を低下させることを明らかにした.","subitem_description_type":"Abstract"}]},"item_5_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"札幌医科大学医学部"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0036-472X","subitem_source_identifier_type":"ISSN"}]},"item_5_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sasaki, Takanori"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-09-28"}],"displaytype":"detail","filename":"13 研究論文紹介_Sasaki.pdf","filesize":[{"value":"808.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"13 研究論文紹介_Sasaki","url":"https://sapmed.repo.nii.ac.jp/record/13760/files/13 研究論文紹介_Sasaki.pdf"},"version_id":"fdd000f8-141e-493e-a72f-7ae409ca55f4"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"technical report","resourceuri":"http://purl.org/coar/resource_type/c_18gh"}]},"item_title":"Microenvironmental stresses induce HLA-E/Qa-1 surface expressionand thereby reduce CD8(+) T-cell recognition of　stressed cells.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Microenvironmental stresses induce HLA-E/Qa-1 surface expressionand thereby reduce CD8(+) T-cell recognition of　stressed cells.","subitem_title_language":"en"}]},"item_type_id":"5","owner":"14","path":["1871"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-04-03"},"publish_date":"2017-04-03","publish_status":"0","recid":"13760","relation_version_is_last":true,"title":["Microenvironmental stresses induce HLA-E/Qa-1 surface expressionand thereby reduce CD8(+) T-cell recognition of　stressed cells."],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-12-13T02:17:12.664907+00:00"}