{"created":"2023-05-15T09:06:17.174375+00:00","id":12927,"links":{},"metadata":{"_buckets":{"deposit":"852e25ba-e2f9-4fa4-b0d1-e08392a9facb"},"_deposit":{"created_by":14,"id":"12927","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"12927"},"status":"published"},"_oai":{"id":"oai:sapmed.repo.nii.ac.jp:00012927","sets":["1875:1978:1980"]},"author_link":["19158","19159","19160"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"83","bibliographicPageStart":"79","bibliographicVolumeNumber":"71","bibliographic_titles":[{"bibliographic_title":"市立札幌病院医誌 = Acta medica nosocomi Sapporo = The Journal of Sapporo City General Hospital"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"移植後リンパ球増殖性疾患(PTLD)は、多くの症例でEpstein-Barr virus(EBV)の初感染あるいは再活性化が関与していることが知られている。しかし、今回EBVの関与が証明されなかったPTLDを経験したため、ここに報告する。症例は64歳の男性で、7年間の血液透析を経て、妻をドナーとした生体腎移植が施行された。免疫抑制薬はシクロスポリン/ミコフェノール酸モフェチル(MMF)/プレドニゾロンの3剤で導入され、以後の経過は良好であった。移植46ヶ月後に右下腹部痛が出現し、造影CTを施行したところ、移植腎上極に長径15cmの腫瘍を認めた。経皮的針生検を施行し、びまん性大細胞型B細胞性リンパ腫と診断された。EBER(EBV-encoded RNA)染色は陰性、EBV-DNAも陰性であり、EBVの関与は証明されなかった。MMFを中止し、R-CHOP(リツキシマブ、シクロフォスファミド、ドキソルビシン、ビンクリスチン、メチルプレドニゾロンによる抗がん剤治療)を6コース施行して完全寛解となった。以後、移植腎機能を喪失することなく、安定して推移している。","subitem_description_type":"Abstract"}]},"item_2_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"市立札幌病院"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0288-6073","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"和田, 吉生"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"堀田, 記世彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高田, 祐輔"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-21"}],"displaytype":"detail","filename":"l425671279.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"l425671279.pdf","url":"https://sapmed.repo.nii.ac.jp/record/12927/files/l425671279.pdf"},"version_id":"7b6acb1c-54ac-4dc5-aca0-3324a7c2bf37"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"腎移植","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"移植後リンパ球増殖性疾患(PTLD)","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Epstein-Barr virus(EBV)","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Epstein-Barr virus陰性の腎移植後リンパ球増殖性疾患の1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Epstein-Barr virus陰性の腎移植後リンパ球増殖性疾患の1例","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"14","path":["1980"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-05-15"},"publish_date":"2014-05-15","publish_status":"0","recid":"12927","relation_version_is_last":true,"title":["Epstein-Barr virus陰性の腎移植後リンパ球増殖性疾患の1例"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-12-13T04:31:06.881818+00:00"}