@article{oai:sapmed.repo.nii.ac.jp:00011291, author = {鈴木, 聡 and 及川, 光照 and 伊東, 民雄 and 佐光, 一也 and 尾崎, 義丸 and 吉永, 智彰 and 西原, 広史 and 田中, 伸哉 and 中村, 博彦}, issue = {1}, journal = {北海道脳神経疾患研究所医誌 = Journal of Hokkaido Brain Research Foundation}, month = {Mar}, note = {Multiple sclerosis (MS) is an autoimmune condition in which the immune system attacks the central nervous system, leading to demyelination in time and space. Tumefactive demyelinating lesions are generally thought of as solitary lesions greater than 2 cm, with MR imaging characteristics mimicking neoplasms. Without a history of multiple sclerosis, surgical biopsy is often performed in suspected tumors. Herein we describe a case of a patient whom over a six-month period developed relapsing-remitting tumefactive MS. Case: A 32-year-old woman presented with progressive left hemiparesis. Magnetic resonance imaging revealed large solitary right periventricular lesions with ring-like enhancement. Open biopsy via craniotomy was performed under the suspicion of tumor. A pathological examination showed massive demyelination. Tumefactive demyelinating lesions will show a good response to corticosteroid therapy with disappearance of the lesions on follow-up imaging.}, pages = {61--64}, title = {腫瘤様様多発性硬化症の一例}, volume = {19}, year = {2009} }