@article{oai:sapmed.repo.nii.ac.jp:00011289,
 author = {尾崎, 充宣 and 伊東, 民雄 and 尾崎, 義丸 and 本庄, 華織 and 福井, 崇人 and 山崎, 貴明 and 佐藤, 憲市 and 瀬尾, 善宣 and 高梨, 正美 and 中村, 博彦},
 issue = {1},
 journal = {北海道脳神経疾患研究所医誌 = Journal of Hokkaido Brain Research Foundation},
 month = {Mar},
 note = {Radiation therapy for brain neoplasms is known to induce major side effects such as radionecrosis and oncogenesis. Secondary tumors are most frequently meningiomas, sarcomas (especially fibrosarcoma), and gliomas. Although radiation-induced osteosarcoma (RIOS) in skulls is a rare complication, the most cases reported are the development in facial bones or paranasal sinuses after radiation therapy for retinoblastomas. We report two cases of radiation-induced osteosarcoma in paranasal sinuses after surgery and radiation for frontal gliomas. One case was received subtotal removal of the astrocytoma Gr. 2 and 54Gy postoperative irradiation. The other case was received subtotal removal of the anaplastic oligoastrocytoma and 56Gy postoperative irradiation. Osteosarcoma occurred in these cases more than ten years after. Radiation-induced osteosarcoma is a well-known but rare complication of radiotherapy for brain neoplasms with a poor prognosis.},
 pages = {53--56},
 title = {前頭葉グリオーマの治療後、副鼻腔に生じた radiation-induced osteosarcomaの2例},
 volume = {19},
 year = {2009}
}