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Although, VS is originated from the vestibular nerve, the reports for vestibular function have been rare so far. But in patients with VS, the dizziness after GK is very uncomfortable symptoms and sometimes affects on ADL of aged patients. We analyzed vestibular function in consecutive 56 cases of VS prospectively before and after GK. Methods: The tumors, ranging from 0.01 - 8.5ml (mean 2.3ml), were treated with GK of marginal dose of 10-13Gy (mean 12Gy) . The vestibular function was evaluated with caloric test, vestibular evoked myogenic potential (VEMP), and stabilometry (Total length, Marginal area) . We also neurologically examined extraocular movement, stepping test, one foot standing test, and arm deviation test before GK. Results: Thirty-nine out of 56 (70%) patients had history of dizziness. Twenty-two patients complained dizziness before GKRS. After treatment, dizziness disappeared in 12 out of 22 (55%) patients, unchanged in 34 out of 56 (61%) patients, and dizziness deteriorated or newly appeared in 10 out of 56 (18%) patients then recovered in 8 out of 10 (80%) patients. In 2 out of 56 (3.6%) patients, dizziness worsened persistently. Positive rates of caloric test before GK, at 1, 6, 12 mos. after GK were 75, 65, 72, 38%, respectively. Positive rates of VEMP before GK, at 6mos. after GK were 36, 29%. Positive rates of caloric test and VEMP were not different statistically before and after GK. Total length and marginal area of stabilometry were almost same value before and after GK. Neurological positive rates of saccadic eye movement, stepping test, one foot standing test, arm deviation test were 93, 81, 89, 91% before GK. Conclusions: Major part of patients were found to have neurologically vestibular dysfunction. GK dose not remarkably affect on the symptoms of dizziness and the vestibular function in patients with VS. Major part of patients who developed dizziness (new or deteriorated) after GK would recover. 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聴神経腫瘍の前庭機能評価 : ガンマナイフ治療前後の検討
https://sapmed.repo.nii.ac.jp/records/8101
https://sapmed.repo.nii.ac.jp/records/8101d9cfbc8a-9f7d-4b6b-a4a7-7009e8dea91f
名前 / ファイル | ライセンス | アクション |
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n134057641317.pdf (2.0 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-03-24 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 聴神経腫瘍の前庭機能評価 : ガンマナイフ治療前後の検討 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | vestibular schwannoma | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | gamma knife | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | vestibular function | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | dizziness | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | stabilometry | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
北條, 敦史
× 北條, 敦史× 福岡, 誠二× 高梨, 正美× 小西, 正訓× 中村, 博彦 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Object: Functional outcome in patients with vestibular schwannomas (VS) treated by gamma knife (GK) has been reported to be excellent, as well as tumor control. Although, VS is originated from the vestibular nerve, the reports for vestibular function have been rare so far. But in patients with VS, the dizziness after GK is very uncomfortable symptoms and sometimes affects on ADL of aged patients. We analyzed vestibular function in consecutive 56 cases of VS prospectively before and after GK. Methods: The tumors, ranging from 0.01 - 8.5ml (mean 2.3ml), were treated with GK of marginal dose of 10-13Gy (mean 12Gy) . The vestibular function was evaluated with caloric test, vestibular evoked myogenic potential (VEMP), and stabilometry (Total length, Marginal area) . We also neurologically examined extraocular movement, stepping test, one foot standing test, and arm deviation test before GK. Results: Thirty-nine out of 56 (70%) patients had history of dizziness. Twenty-two patients complained dizziness before GKRS. After treatment, dizziness disappeared in 12 out of 22 (55%) patients, unchanged in 34 out of 56 (61%) patients, and dizziness deteriorated or newly appeared in 10 out of 56 (18%) patients then recovered in 8 out of 10 (80%) patients. In 2 out of 56 (3.6%) patients, dizziness worsened persistently. Positive rates of caloric test before GK, at 1, 6, 12 mos. after GK were 75, 65, 72, 38%, respectively. Positive rates of VEMP before GK, at 6mos. after GK were 36, 29%. Positive rates of caloric test and VEMP were not different statistically before and after GK. Total length and marginal area of stabilometry were almost same value before and after GK. Neurological positive rates of saccadic eye movement, stepping test, one foot standing test, arm deviation test were 93, 81, 89, 91% before GK. Conclusions: Major part of patients were found to have neurologically vestibular dysfunction. GK dose not remarkably affect on the symptoms of dizziness and the vestibular function in patients with VS. Major part of patients who developed dizziness (new or deteriorated) after GK would recover. Stabilometry seems to be a good tool to evaluate dizziness before and after GK. | |||||
書誌情報 |
北海道脳神経疾患研究所医誌 = Journal of Hokkaido Brain Research Foundation 巻 13, 号 1, p. 7-13, 発行日 2003-03-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1340-5764 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
その他のタイトル | ||||||
その他のタイトル | Vestibular Function in Cases with Vestibular Schwannomas Treated by Gamma Knife | |||||
出版者 | ||||||
出版者 | 中村記念病院 |