WEKO3
-
RootNode
アイテム
癌病変に伴う末梢神経障害 : 特に血中葉酸濃度との関係について II. ラット肝癌についての動物実験
https://doi.org/10.15114/smj.49.72
https://doi.org/10.15114/smj.49.726b869c7c-4c83-4a5c-84ba-275fec8a2770
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
n0036472X49172.pdf (3.8 MB)
|
|
| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2019-08-23 | |||||||
| タイトル | ||||||||
| タイトル | 癌病変に伴う末梢神経障害 : 特に血中葉酸濃度との関係について II. ラット肝癌についての動物実験 | |||||||
| 言語 | ja | |||||||
| タイトル | ||||||||
| タイトル | Neuropathy Associated with Cancers with an Emphasis on Nerve Conduction Velocity and Serum Folate Level. II. Studies on Experimental Hepatoma of the Rats | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | jpn | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| ID登録 | ||||||||
| ID登録 | 10.15114/smj.49.72 | |||||||
| ID登録タイプ | JaLC | |||||||
| 著者 |
千葉, 進
× 千葉, 進
|
|||||||
| 著者別名 | ||||||||
| 識別子Scheme | WEKO | |||||||
| 識別子 | 28365 | |||||||
| 姓名 | Susumu, Chiba | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Hepatoma was prepared by the administration of 3'-Me-DAB to the rats in order to study the pathophysiology of experimental carcinomatous neuropathy, which was quantitatively analyzed by nerve conduction velocity of dorsal nerve trunks with an assessment of histological examination of the sciatic nerve and was also simultaneously investigated in terms of folate metabolism. 1. The motor nerve conduction velocity, which was markedly delayed from the early stage of hepatoma, did not show a close correlation with the progress of hepatoma. 2. The teased fiber of the sciatic nerve demonstrated degenerative changes of myelin sheath at the paranodal area of Ranvier reflecting delayed nerve conduction velocity. 3. The hepatoma rats revealed low serum folate levels, and the folate concentration fell in accordance with hepatoma progress in the liver, spleen, kidney as well as blood. 4. The motor nerve conduction velocity and serum folate level were interrelated as a whole including normal and hepatoma rats. 5. The folate administered hepatoma rats were prevented from delaying the motor nerve conduction velocity with normal serum serine/glycine ratio. 6. From the above results, it was conjectured that folate deficiency probably play an important role in developing carcinomatous neuropathy. | |||||||
| 書誌情報 |
札幌医学雑誌 = The Sapporo medical journal en : The Sapporo medical journal 巻 49, 号 1, p. 72-80, 発行日 1980-02-01 |
|||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0036-472X | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| 出版者 | ||||||||
| 出版者 | 札幌医科大学医学部 | |||||||
