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癌遺伝子によるマウス骨芽細胞株MC3T3-E1のトランスフォーメーショソ
https://doi.org/10.15114/smj.60.233
https://doi.org/10.15114/smj.60.2333c57cbbd-32bb-48ac-83d6-3fb425af90c4
名前 / ファイル | ライセンス | アクション |
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n0036472X603233.pdf (3.5 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2019-07-31 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 癌遺伝子によるマウス骨芽細胞株MC3T3-E1のトランスフォーメーショソ | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Transformation of Osteoblastic Cell Line MC3T3-E1 with Oncogenes | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Yamashita, Toshiharu | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Osteoblast | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Oncogene | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Transformation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Alkaline phosphatase | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.15114/smj.60.233 | |||||
ID登録タイプ | JaLC | |||||
著者 |
斉藤, 要一
× 斉藤, 要一× 吉田, 幸一× 山下, 利春 |
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著者別名 | ||||||
姓名 | Saito, Yoichi | |||||
著者別名 | ||||||
姓名 | Yoshida, Koichi | |||||
著者別名 | ||||||
姓名 | Yamashita, Tshiharu | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Several oncogenes were introduced into a normal mouse osteoblastic cell line, MC3T3- El, by calcium phosphate-mediated DNA transfection. Transformed foci were formed by cotransfection with adenovirus type 12 E1A (Adl2E1A) and activated c-Ha-ras (EJras) oncogenes, and with c-myc and EJras oncogenes. Transfection with c- myc, Ad12E1A or EJras induced no obvious foci. Transformed cell lines established from each trans- formed focus had high saturation densities in culture and were tumorigenic when injected into athy- mic mice with low-differetiated sarcoma. The transfected oncogene DNA sequences were detected in the cellular DNA of all the transformants. Alkaline phosphatase activity decreased in transformants compared to their parental MC3T3-E1 cells. | |||||
書誌情報 |
札幌医学雑誌 = The Sapporo medical journal en : The Sapporo medical journal 巻 60, 号 3, p. 233-240, 発行日 1991-06-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0036-472X | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 札幌医科大学医学部 |