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胃潰瘍治癒過程における神経細胞接着分子 (NCAM) の発現
https://doi.org/10.15114/smj.64.189
https://doi.org/10.15114/smj.64.18974099749-28a9-4a59-a729-7e8cc546a1f8
名前 / ファイル | ライセンス | アクション |
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n0036472X645189.pdf (2.7 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2019-07-31 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 胃潰瘍治癒過程における神経細胞接着分子 (NCAM) の発現 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The Expression of Neural Cell Adhesion Molecule (NCAM) during the Healing Process of Gastric Ulcer | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | NCAM | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Gastric ulcer | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Adhesion molecule | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Healing process | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.15114/smj.64.189 | |||||
ID登録タイプ | JaLC | |||||
著者 |
一柳, 伸吾
× 一柳, 伸吾× 杉山, 敏郎× 矢花, 剛 |
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著者別名 | ||||||
姓名 | Ichiyanagi, Shingo | |||||
著者別名 | ||||||
姓名 | Sugiyama, Toshiro | |||||
著者別名 | ||||||
姓名 | Yabana, Tsuyoshi | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Neural cell adhesion molecule (NCAM) is a glycoprotein, which belongs to the immunoglobulin superfamily and functions as homophilic adhesion molecule and is considered to play an important role in cell formation and tissue structure. NCAM is mainly expressed on neurogenic cells, myogenic cells and NK cells, but there is no report that NCAM is expressed on the gastric mucosal epithelium. In this study, we investigated the expression of NCAM in the healing process of human gastric ulcer and rat acetic acid induced ulcer with immunohistological methods, the reverse transcriptase-polymerase chain reaction (RT-PCR) and Southern blot analysis. The results were as follows. 1) Immunohistologically NCAM was expressed in the gastric mucosal epithelium in human gastric ulcer and rat acetic acid induced ulcer in the healing stage. 2) NCAM was also expressed in the fraction of gastric mucosa adjacent to the ulcer by dot blot analysis. 3) RT-PCR and Southern blot analysis revealed that NCAM mRNA was expressed in the gastric mucosa in the healing stage and it contained a transmembrane domain, suggesting that it plays an important role in mucosal repair of gastric ulcer. | |||||
書誌情報 |
札幌医学雑誌 = The Sapporo medical journal en : The Sapporo medical journal 巻 64, 号 5, p. 189-196, 発行日 1995-10-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0036-472X | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 札幌医科大学医学部 |