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Exploitation of Melanin and Melanosome Biogenesis for Better Management of Malignant Melanoma
https://doi.org/10.15114/smj.74.23
https://doi.org/10.15114/smj.74.23c5ce4c9b-5d2d-41d1-801b-f8e6cd148d63
名前 / ファイル | ライセンス | アクション |
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n0036472X74323.pdf (386.7 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2019-07-31 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Exploitation of Melanin and Melanosome Biogenesis for Better Management of Malignant Melanoma | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Melanoma | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Skin cancer | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Melanin | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Melanosome | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Chemotherapy | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Immunotherapy | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Epidemiology | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Nano-medicine | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.15114/smj.74.23 | |||||
ID登録タイプ | JaLC | |||||
著者 |
神保, 孝一
× 神保, 孝一× 山下, 利春× 松坂, 英信× 廣崎, 邦紀× 米田, 明弘× 鎌田, 麻子× 井上, 裕悦× 肥田, 時征× 川上, 聡経 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Management of malignant melanoma is a difficult challenge for physicians and basic scientists because cutaneous melanoma grows in the highly vascular tissue of epidermo-dermal interface and occurs at any age of generation. It can easily spread to distant organs and practically no treatment modality is available except for early diagnosis and surgical excision. In this report we review our current research efforts in establishing novel diagnostic and therapeutic approaches for malignant melanoma by exploiting our knowledge of basic biology in melanin and melanosome biogenesis. This is based upon the fact that melanin and melanosome biogenesis is biological property uniquely expressed in melanocytes, and highly accelerated and altered in their neoplastic counterpart, malignant melanoma. It is immediately apparent if one looks at the past literatures that rapid and significant progress of cancer management has been made if the biological property unique to cancer cells is exploited. | |||||
書誌情報 |
札幌医学雑誌 = The Sapporo medical journal en : The Sapporo medical journal 巻 74, 号 3, p. 23-31, 発行日 2005-08-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0036-472X | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 札幌医科大学医学部 |